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Semaglutide absorption occurs mostly in the stomach and intestines, and anything that slows down or alters stomach function could theoretically change how quickly the drug enters the bloodstream
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Specifically, Figure S3A shows the LC/MS results, where the molecular weights corresponding to charge states [M+3] 3+ , [M+4] 4+ , and [M+5] 5+ were 1103.54, 827.91, and 662.53 Da, respectively